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Disease Profile
Zika virus infection
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.
Unknown
Age of onset
All ages
ICD-10
U06
Inheritance
Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.
Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.
X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.
X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.
Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.
Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.
Not applicable
Other names (AKA)
Zika fever; Zika virus disease
Categories
Viral infections
Summary
Zika
Diagnosis
Making a diagnosis for a genetic or rare disease can often be challenging. Healthcare professionals typically look at a person’s medical history, symptoms, physical exam, and laboratory test results in order to make a diagnosis. The following resources provide information relating to diagnosis and testing for this condition. If you have questions about getting a diagnosis, you should contact a healthcare professional.
Testing Resources
- The Centers for Disease Control and Prevention has information on diagnostic testing for Zika
virus infection. - The Centers for Disease Control and Prevention has a feature which allows individuals to find their state health department
Treatment
In pregnant women with evidence of Zika virus in the blood or amniotic fluid, serial ultrasounds should be considered to monitor fetal anatomy and growth every 3-4 weeks. Referral to a maternal-fetal medicine specialist or
Management Guidelines
- The Center for Disease Control and Prevention (CDC) has posted interim guidelines for pregnant women during the Zika virus outbreak.
- The Centers for Disease Control and Prevention has posted Interim Guidelines for Health Care Providers Caring for Pregnant Women and Women of Reproductive Age with Possible Zika Virus Exposure.
Organizations
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Organizations Providing General Support
-
Centers for Disease Control and Prevention
1600 Clifton Road
Atlanta, GA 30329-4027
Toll-free: 800-CDC-INFO
TTY: 888-232-6348
Website: https://www.cdc.gov/
Learn more
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Where to Start
- You can obtain general information on this topic from the Centers for Disease Control and Prevention (CDC). The CDC is recognized as the lead federal agency for developing and applying disease prevention and control measures to improve the health of the people of the United States. The CDC has updated information and videos on the Zika virus.
- The March of Dimes has information on Zika virus and pregnancy.
- MotherToBaby is a service of the non-profit Organization of Teratology Information Specialists (OTIS), a leading authority on information regarding the safety of medications and other exposures during pregnancy and breastfeeding. They can be reached directly by calling 1-866-626-6847.
- The World Health Organization (WHO) produces guidelines and standards, helps countries to address public health issues, and supports and promotes health research. The WHO has developed a fact sheet on this condition.
In-Depth Information
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
References
- Transmission & Risks. Centers for Disease Control and Prevention (CDC). March 3, 2016; https://www.cdc.gov/zika/transmission/index.html.
- Areas with Zika. Centers for Disease Control and Prevention. Centers for Disease Control and Prevention (CDC). February 9, 2016; https://www.cdc.gov/zika/geo/index.html.
- Zika Virus. Centers for Disease Control and Prevention (CDC) Newsroom. April 13, 2016; https://www.cdc.gov/media/dpk/2016/dpk-zika-virus.html.
- Zika and Guillain-Barré Syndrome. Centers for Disease Control and Prevention (CDC). August 9, 2016; https://www.cdc.gov/zika/healtheffects/gbs-qa.html.
- Rasmussen, Sonja, et al.. Zika Virus and Birth Defects — Reviewing the Evidence for Causality. New England Journal of Medicine Special Report. April 13, 2016; https://www.nejm.org/doi/pdf/10.1056/NEJMsr1604338. Accessed 4/13/2016.
- How to Protect Yourself. Centers for Disease Control and Prevention (CDC). March 18, 2016; https://www.cdc.gov/zika/pregnancy/protect-yourself.html.
- Zika Virus: Symptoms & Treatment. Centers for Disease Control and Prevention (CDC). December 28, 2015; https://www.cdc.gov/zika/symptoms/index.html. Accessed 1/14/2016.
- Zika Virus For Health Care Providers: Clinical Evaluation & Disease. Centers for Disease Control and Prevention (CDC). June 1, 2015; https://www.cdc.gov/zika/hc-providers/clinicalevaluation.html. Accessed 1/14/2016.
- Interim Guidelines for Pregnant Women During a Zika Virus Outbreak — United States, 2016. Centers for Disease Control and Prevention MMWR. January 19, 2016; Vol.65:https://www.cdc.gov/mmwr/volumes/65/wr/pdfs/mm6502e1er.pdf. Accessed 3/4/2016.
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